Conformational gating of dimannose binding to the antiviral protein cyanovirin revealed from the crystal structure at 1.35 Å resolution

Keyphrases

• Binding Site 100%
• Complex Structure 100%
• Cyanovirin-N 100%
• Antiviral Protein 100%
• Conformational Gating 100%
• High Affinity 50%
• Molecular Dynamics Simulation 50%
• Time Regime 50%
• HIV Infection 50%
• Mannose 50%
• Lectin 50%
• Gp120 50%
• Locking Mechanism 50%
• Experimental Support 50%
• NMR Structure 50%
• Antiviral Activity 50%
• Oligosaccharides 50%
• Gating Mechanism 50%
• Binding Conformation 50%
• Quasi-symmetric 50%
• Multivalent Binding 50%
• Neutralization Activity 50%
• Mannose-binding 50%
• Mucosal Defense 50%
• Oligomannosides 50%
• HIV Neutralization 50%

Biochemistry, Genetics and Molecular Biology

• Crystal Structure 100%
• Conformation 100%
• Wild Type 100%
• Human Immunodeficiency Virus 100%
• Binding Site 100%
• Antiviral Protein 100%
• Mannose 100%
• Lectin 50%
• Antiviral Activity 50%
• Oligosaccharide 50%
• Computer Simulation 50%

Immunology and Microbiology

• Wild Type 100%
• Binding Site 100%
• Crystal Structure 100%
• Conformation 100%
• Human Immunodeficiency Virus Infection 50%
• Human Immunodeficiency Virus 50%
• Lectin 50%
• Neutralization 50%
• Antiviral Activity 50%
• Computer Simulation 50%