Wireless neural recording with single low-power integrated circuit

Reid R. Harrison, Ryan J. Kier, Cynthia A. Chestek, Vikash Gilja, Paul Nuyujukian, Stephen Ryu, Bradley Greger, Florian Solzbacher, Krishna V. Shenoy

Research output: Contribution to journalArticlepeer-review

169 Scopus citations


We present benchtop and in vivo experimental results from an integrated circuit designed for wireless implantable neural recording applications. The chip, which was fabricated in a commercially available 0.6-μm 2P3M BiCMOS process, contains 100 amplifiers, a 10-bit analog-to-digital converter (ADC), 100 threshold-based spike detectors, and a 902-928 MHz frequency-shift-keying (FSK) transmitter. Neural signals from a selected amplifier are sampled by the ADC at 15.7 kSps and telemetered over the FSK wireless data link. Power, clock, and command signals are sent to the chip wirelessly over a 2.765-MHz inductive (coil-to-coil) link. The chip is capable of operating with only two off-chip components: a power/command receiving coil and a 100-nF capacitor.

Original languageEnglish (US)
Pages (from-to)322-329
Number of pages8
JournalIEEE Transactions on Neural Systems and Rehabilitation Engineering
Issue number4
StatePublished - Aug 2009
Externally publishedYes


  • Brain-machine interface (BMI)
  • Low power
  • Neural prosthetics
  • Telemetry
  • Wireless

ASJC Scopus subject areas

  • Internal Medicine
  • General Neuroscience
  • Biomedical Engineering


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