Vitamin C

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations


Vitamin C is a potent reducing agent in mammals and plants. Humans rely on vitamin C for the activity of numerous enzymes, and vitamin C status impacts physiological health, including risk for infections, cardiovascular disease, and cancer. The recommended intake for vitamin C in adults varies by gender and by country (from 45 to 110mg/d). The Tolerable Upper Intake Level is 2000mg/d. Supplemental vitamin C should not replace high intakes of fruits and vegetables, but it may offer health benefits under certain circumstances. Low intake of fruits and vegetables increases risk for scurvy, a concern for isolated populations, refugees, the critically ill, and the elderly. Smokers and patient populations are also at risk for suboptimal vitamin C status. Current vitamin C deficiency rates in developed countries range from 8% to 19%. Individuals with a history of renal stone formation or conditions associated with iron overload should use caution when supplementing with vitamin C.

Original languageEnglish (US)
Title of host publicationPresent Knowledge in Nutrition
Subtitle of host publicationBasic Nutrition and Metabolism
Number of pages15
ISBN (Electronic)9780323661621
ISBN (Print)9780128198421
StatePublished - Jan 1 2020


  • Antioxidant
  • Immunoenhancement
  • Injection therapy
  • Scurvy
  • Vascular health

ASJC Scopus subject areas

  • General Health Professions
  • General Medicine


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