1 Scopus citations


Several randomized controlled intervention trials have reported improvements in mood following the adoption of vegetarian diets. However, mechanisms contributing to this improvement have not been investigated. Mood is regulated by the action of the neurotransmitters serotonin and norepinephrine and the proinflammatory cytokines (e.g., IL-1β, TNF-α, IL-6, and IL-2) and eicosanoids (e.g., PGE2). Vegetarian diets are inherently rich in antioxidants, and adherence to vegetarian diets is associated with low oxidative stress and PGE2 concentrations. Furthermore, the high carbohydrate-to-protein ratio of vegetarian diets should facilitate tryptophan entry into the brain and the production of serotonin. This chapter explores the aspects of vegetarian diets that would theoretically promote healthful mood states by promoting neurotransmitter action.

Original languageEnglish (US)
Title of host publicationVegetarian and Plant-Based Diets in Health and Disease Prevention
PublisherElsevier Inc.
Number of pages17
ISBN (Electronic)9780128039694
ISBN (Print)9780128039687
StatePublished - May 30 2017


  • Mood state
  • PGE
  • Proinflammatory cytokines
  • Serotonin
  • Vegetarian diet

ASJC Scopus subject areas

  • General Engineering
  • General Agricultural and Biological Sciences


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