Unidirectional scaffold-strand arrangement in DNA origami

Dongran Han, Shuoxing Jiang, Anirban Samanta, Yan Liu, Hao Yan

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


In a parallel universe: DNA origami structures based on modified parallel double-crossover tiles (see scheme) were constructed and a unidirectional (parallel) arrangement of the scaffold strand (gray lines) was used in the assembly of a variety of 2D and 3D DNA origami structures. This will greatly expand the diversity of DNA origami and enable their assembly into larger structures.

Original languageEnglish (US)
Pages (from-to)9031-9034
Number of pages4
JournalAngewandte Chemie - International Edition
Issue number34
StatePublished - Aug 19 2013


  • DNA nanotechnology
  • DNA origami
  • nanostructures
  • parallel DNA crossover
  • self-assembly

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)


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