TY - GEN
T1 - Tiamat
T2 - 14th International Meeting on DNA Computing, DNA14
AU - Williams, Sean
AU - Lund, Kyle
AU - Lin, Chenxiang
AU - Wonka, Peter
AU - Lindsay, Stuart
AU - Yan, Hao
N1 - Copyright:
Copyright 2009 Elsevier B.V., All rights reserved.
PY - 2009
Y1 - 2009
N2 - We present the development of a new graphical user interface driven molecular modeling, editing and visualization tool called Tiamat. Tiamat addresses the challenge of how to efficiently model large and complex DNA nanostructures. We describe the three major components of our system. First, we discuss design guidelines and data structures that form the basis of flexible and large-scale editing. Second, we explain a semi-automatic sequence generator that combines user input with random sequence generation to efficiently label the molecules in the DNA structure. Third, we outline the visualization techniques including a simplification algorithm that are used to render large designs. The results demonstrate how Tiamat was used to generate large and complex designs.
AB - We present the development of a new graphical user interface driven molecular modeling, editing and visualization tool called Tiamat. Tiamat addresses the challenge of how to efficiently model large and complex DNA nanostructures. We describe the three major components of our system. First, we discuss design guidelines and data structures that form the basis of flexible and large-scale editing. Second, we explain a semi-automatic sequence generator that combines user input with random sequence generation to efficiently label the molecules in the DNA structure. Third, we outline the visualization techniques including a simplification algorithm that are used to render large designs. The results demonstrate how Tiamat was used to generate large and complex designs.
KW - 3D DNA structure display
KW - DNA sequence design
KW - DNA tile
KW - Structural DNA nanotechnology
UR - http://www.scopus.com/inward/record.url?scp=70450201951&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=70450201951&partnerID=8YFLogxK
U2 - 10.1007/978-3-642-03076-5_8
DO - 10.1007/978-3-642-03076-5_8
M3 - Conference contribution
AN - SCOPUS:70450201951
SN - 3642030750
SN - 9783642030758
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 90
EP - 101
BT - DNA Computing - 14th International Meeting on DNA Computing, DNA14, Revised Selected Papers
Y2 - 2 June 2008 through 9 June 2008
ER -