Three new alkaloids, convolutamines F and G, and convolutamydine E, from the Floridian marine bryozoan Amathia convoluta

Yoshiaki Kamano; Ayano Kotake; Hirofumi Hashima; Ichiro Hayakawa; Hatsue Hiraide; Hui Ping Zhang; Haruhisa Kizu; Kanki Komiyama; Masahiko Hayashi; George Pettit

doi:10.1135/cccc19991147

Three new alkaloids, convolutamines F and G, and convolutamydine E, from the Floridian marine bryozoan Amathia convoluta

Yoshiaki Kamano, Ayano Kotake, Hirofumi Hashima, Ichiro Hayakawa, Hatsue Hiraide, Hui Ping Zhang, Haruhisa Kizu, Kanki Komiyama, Masahiko Hayashi, George Pettit

Molecular Sciences, School of (SMS)

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Abstract

Two new (2-phenylethyl)amine alkaloids, convolutamines F and G, and a dibromohydroxy-oxindole alkaloid, convolutamydine E, have been isolated from the butan-1-ol soluble material of the Floridian marine bryozoan Amathia convoluta. Their structures were elucidated on the basis of spectroscopic data. Convolutamine F exhibited activity against KB, KB/VJ-300, and U937 cells. This compound also exhibited the inhibitory effects for cell division of fertilized sea urchin eggs.

Original language	English (US)
Pages (from-to)	1147-1153
Number of pages	7
Journal	Collection of Czechoslovak Chemical Communications
Volume	64
Issue number	7
DOIs	https://doi.org/10.1135/cccc19991147
State	Published - Jan 1 1999

Keywords

(2-phenylethyl)amine alkaloids
3-hydroxyindol-2(3H)-one
Amathia convoluta
Bryozoa
Convolutamine F
Convolutamine G
Convolutamydine E
Cytostatic activity
Isolation
Marine natural products

ASJC Scopus subject areas

Chemistry(all)

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10.1135/cccc19991147

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title = "Three new alkaloids, convolutamines F and G, and convolutamydine E, from the Floridian marine bryozoan Amathia convoluta",

abstract = "Two new (2-phenylethyl)amine alkaloids, convolutamines F and G, and a dibromohydroxy-oxindole alkaloid, convolutamydine E, have been isolated from the butan-1-ol soluble material of the Floridian marine bryozoan Amathia convoluta. Their structures were elucidated on the basis of spectroscopic data. Convolutamine F exhibited activity against KB, KB/VJ-300, and U937 cells. This compound also exhibited the inhibitory effects for cell division of fertilized sea urchin eggs.",

keywords = "(2-phenylethyl)amine alkaloids, 3-hydroxyindol-2(3H)-one, Amathia convoluta, Bryozoa, Convolutamine F, Convolutamine G, Convolutamydine E, Cytostatic activity, Isolation, Marine natural products",

author = "Yoshiaki Kamano and Ayano Kotake and Hirofumi Hashima and Ichiro Hayakawa and Hatsue Hiraide and Zhang, {Hui Ping} and Haruhisa Kizu and Kanki Komiyama and Masahiko Hayashi and George Pettit",

year = "1999",

month = jan,

day = "1",

doi = "10.1135/cccc19991147",

language = "English (US)",

volume = "64",

pages = "1147--1153",

journal = "Collection of Czechoslovak Chemical Communications",

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TY - JOUR

T1 - Three new alkaloids, convolutamines F and G, and convolutamydine E, from the Floridian marine bryozoan Amathia convoluta

AU - Kamano, Yoshiaki

AU - Kotake, Ayano

AU - Hashima, Hirofumi

AU - Hayakawa, Ichiro

AU - Hiraide, Hatsue

AU - Zhang, Hui Ping

AU - Kizu, Haruhisa

AU - Komiyama, Kanki

AU - Hayashi, Masahiko

AU - Pettit, George

PY - 1999/1/1

Y1 - 1999/1/1

N2 - Two new (2-phenylethyl)amine alkaloids, convolutamines F and G, and a dibromohydroxy-oxindole alkaloid, convolutamydine E, have been isolated from the butan-1-ol soluble material of the Floridian marine bryozoan Amathia convoluta. Their structures were elucidated on the basis of spectroscopic data. Convolutamine F exhibited activity against KB, KB/VJ-300, and U937 cells. This compound also exhibited the inhibitory effects for cell division of fertilized sea urchin eggs.

AB - Two new (2-phenylethyl)amine alkaloids, convolutamines F and G, and a dibromohydroxy-oxindole alkaloid, convolutamydine E, have been isolated from the butan-1-ol soluble material of the Floridian marine bryozoan Amathia convoluta. Their structures were elucidated on the basis of spectroscopic data. Convolutamine F exhibited activity against KB, KB/VJ-300, and U937 cells. This compound also exhibited the inhibitory effects for cell division of fertilized sea urchin eggs.

KW - (2-phenylethyl)amine alkaloids

KW - 3-hydroxyindol-2(3H)-one

KW - Amathia convoluta

KW - Bryozoa

KW - Convolutamine F

KW - Convolutamine G

KW - Convolutamydine E

KW - Cytostatic activity

KW - Isolation

KW - Marine natural products

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U2 - 10.1135/cccc19991147

DO - 10.1135/cccc19991147

M3 - Article

AN - SCOPUS:0001189019

SN - 0010-0765

VL - 64

SP - 1147

EP - 1153

JO - Collection of Czechoslovak Chemical Communications

JF - Collection of Czechoslovak Chemical Communications

IS - 7

ER -

Three new alkaloids, convolutamines F and G, and convolutamydine E, from the Floridian marine bryozoan Amathia convoluta

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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