The similarity index and DNA fingerprinting

Research output: Contribution to journalArticlepeer-review

578 Scopus citations


DNA-fingerprint similarity is being used increasingly to make inferences about levels of genetic variation within and between natural populations. It is shown that the similarity index - the average fraction of shared restriction fragments - provides upwardly biased estimates of population homozygosity but nearly unbiased estimates of the average identity-in-state for random pairs of individuals. A method is suggested for partitioning the DNA-fingerprint dissimilarity into within- and between-population components. Some simple expressions are given for the sampling variances of these estimators.

Original languageEnglish (US)
Pages (from-to)478-484
Number of pages7
JournalMolecular biology and evolution
Issue number5
StatePublished - 1990
Externally publishedYes


  • Dna fingerprinting
  • Population genetic analysis

ASJC Scopus subject areas

  • Genetics
  • Ecology, Evolution, Behavior and Systematics
  • Molecular Biology


Dive into the research topics of 'The similarity index and DNA fingerprinting'. Together they form a unique fingerprint.

Cite this