The evolvability of lead peptides from small library screens

Jinglei Zhang, Berea A R Williams, Mikael T. Nilsson, John C. Chaput

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Very little is known about the evolvability of lead peptides that are isolated from small library screens. Here we begin to explore this question by comparing the directed evolution of two peptides previously isolated from a small library screen to new ligands generated de novo by in vitro selection.

Original languageEnglish (US)
Pages (from-to)7778-7780
Number of pages3
JournalChemical Communications
Issue number41
StatePublished - Nov 7 2010

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • General Chemistry
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry


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