TY - JOUR
T1 - The association between physical activity, cardiorespiratory fitness, and lipoprotein(a) concentrations in a tri-ethnic sample of women
T2 - The cross-cultural activity participation study
AU - Drowatzky, Katrina L.
AU - Durstine, J. Larry
AU - Irwin, Melinda L.
AU - Moore, Charity G.
AU - Davis, Paul G.
AU - Hand, Gregory A.
AU - Gonzalez, M. Francisco
AU - Ainsworth, Barbara E.
PY - 2001
Y1 - 2001
N2 - The purpose of this cross-sectional study was threefold: (1) to examine ethnic differences in plasma lipoprotein(a) [Lp(a)] concentrations; (2) to examine the relationship between physical activity levels (moderate, moderate-vigorous, and total MET-min/day) and Lp(a) concentrations; and (3) to determine the relationship between maximal treadmill time and Lp(a) concentrations among African-American, Native American, and Caucasian women (n = 140, ages 40-70 years: 54.5±10.7). Physical activity records were kept for two 4-day periods, scheduled 1 month apart, a total of 8 days, and each activity was assigned a code from the 'Compendium of physical activity'. Subjects completed a graded exercise test to determine maximal treadmill time, and a fasted blood sample was collected to quantify Lp(a) concentration. Lp(a) concentrations were negatively skewed with a geometric mean of 28.3 mg/dl (25-75%: 10.4-43.1 mg/dl) in African-Americans (n = 47), 2.9 mg/dl (25-75%: 1.2-7.4 mg/dl) in Native Americans (n = 45), and 9.4 mg/dl (25-75%: 2.6-22.4 mg/dl) in Caucasians (n = 48). African-American women had significantly higher (p<0.05) Lp(a) concentrations than either Native Americans or Caucasians. No relationships were observed among moderate, moderate-vigorous, and total MET-min/day of physical activity, maximal treadmill time, and Lp(a) concentrations. Significant ethnic differences in Lp(a) concentrations were found, with African-American women having higher Lp(a) concentrations than Native American and Caucasian women. Lp(a) concentrations were not associated with any physical activity variables. Therefore, physical activity and maximal treadmill time did not influence Lp(a) concentrations in this tri-ethnic population of women.
AB - The purpose of this cross-sectional study was threefold: (1) to examine ethnic differences in plasma lipoprotein(a) [Lp(a)] concentrations; (2) to examine the relationship between physical activity levels (moderate, moderate-vigorous, and total MET-min/day) and Lp(a) concentrations; and (3) to determine the relationship between maximal treadmill time and Lp(a) concentrations among African-American, Native American, and Caucasian women (n = 140, ages 40-70 years: 54.5±10.7). Physical activity records were kept for two 4-day periods, scheduled 1 month apart, a total of 8 days, and each activity was assigned a code from the 'Compendium of physical activity'. Subjects completed a graded exercise test to determine maximal treadmill time, and a fasted blood sample was collected to quantify Lp(a) concentration. Lp(a) concentrations were negatively skewed with a geometric mean of 28.3 mg/dl (25-75%: 10.4-43.1 mg/dl) in African-Americans (n = 47), 2.9 mg/dl (25-75%: 1.2-7.4 mg/dl) in Native Americans (n = 45), and 9.4 mg/dl (25-75%: 2.6-22.4 mg/dl) in Caucasians (n = 48). African-American women had significantly higher (p<0.05) Lp(a) concentrations than either Native Americans or Caucasians. No relationships were observed among moderate, moderate-vigorous, and total MET-min/day of physical activity, maximal treadmill time, and Lp(a) concentrations. Significant ethnic differences in Lp(a) concentrations were found, with African-American women having higher Lp(a) concentrations than Native American and Caucasian women. Lp(a) concentrations were not associated with any physical activity variables. Therefore, physical activity and maximal treadmill time did not influence Lp(a) concentrations in this tri-ethnic population of women.
KW - African-American
KW - Lipoprotein(a)
KW - Native American
KW - Physical activity
KW - Women
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U2 - 10.1191/135886301675452295
DO - 10.1191/135886301675452295
M3 - Article
C2 - 11358155
AN - SCOPUS:0035025822
SN - 1358-863X
VL - 6
SP - 15
EP - 21
JO - Vascular Medicine
JF - Vascular Medicine
IS - 1
ER -