Synthetic biology strategies to address waste CO2 loss during biofuel production

Amanda Godar, Cody Kamoku, David Nielsen, Xuan Wang

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


Owing to differing degrees of reduction between substrates and products, biofuel production from carbohydrates inevitably releases a significant amount of CO2, reducing both overall carbon utilization efficiency and the sustainability of biofuel production processes. To address this fundamental and persistent challenge, recent studies have explored diverse metabolic engineering and synthetic biology approaches to either i) limit CO2 evolution by decreasing its generation or ii) recycle it through various biochemical mechanisms. Through these strategies, carbon that would have been wasted as CO2 is reduced, allowing carbon conversion efficiency to be significantly enhanced and greenhouse gas emission effectively mitigated, thus potentially leading to a more sustainable microbial process for biofuel production.

Original languageEnglish (US)
Article number100305
JournalCurrent Opinion in Environmental Science and Health
StatePublished - Dec 2021


  • Biofuel
  • CO
  • Carbon conservation
  • Sustainability
  • Synthetic biology

ASJC Scopus subject areas

  • Environmental Chemistry
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis


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