Abstract
Surface plasmon resonance microscopy (SPRM) is a versatile platform for chemical and biological sensing and imaging. Great progress in exploring its applications, ranging from single-molecule sensing to single-cell imaging, has been made. In this Minireview, we introduce the principles and instrumentation of SPRM. We also summarize the broad and exciting applications of SPRM to the analysis of single entities. Finally, we discuss the challenges and limitations associated with SPRM and potential solutions.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1776-1785 |
| Number of pages | 10 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 59 |
| Issue number | 5 |
| DOIs | |
| State | Published - Jan 27 2020 |
Keywords
- binding kinetics
- label-free methods
- sensors
- single-cell imaging
- surface plasmon resonance
ASJC Scopus subject areas
- Catalysis
- General Chemistry