Stylopeptide 2, a proline-rich cyclodecapeptide from the sponge Stylotella sp.

Mary R. Brennan, Catherine E. Costello, Simin D. Maleknia, George Pettit, Karen L. Erickson

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


A new proline-rich cyclodecapeptide, designated stylopeptide 2, has been isolated from a cytotoxic extract of the Papua New Guinea marine sponge Stylotella sp. and found to correspond to structure 1. The structural assignment was based on HRMS collision-induced dissociation tandem mass spectrometry (CID MS/MS), NMR spectroscopic data, and amino acid analysis, which led to assignment of the absolute configuration.

Original languageEnglish (US)
Pages (from-to)453-456
Number of pages4
JournalJournal of Natural Products
Issue number3
StatePublished - Mar 2008

ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry


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