@article{de39c72b90064c428e0ac5aff3e404db,
title = "Structure-guided identification of a peptide for bio-enabled gold nanoparticle synthesis",
abstract = "In this study, we show that maltose-binding protein (MBP) is capable of facilitating stable gold nanoparticle synthesis, and a structure of MBP in the presence of gold ions was determined by X-ray crystallography. Using this high-resolution structure of gold ion bound MBP, a peptide (AT1) was selected and synthesized and was shown to also aid in the synthesis of stable gold nanoparticles under similar experimental conditions to those used for protein facilitated synthesis. This structure-based approach represents a new potential method for the selection of peptides capable of facilitating stable nanoparticle synthesis.",
keywords = "biomineralization, gold nanoparticles, nanobiotechnology, protein crystallography",
author = "Amar Thaker and Luqmanal Sirajudeen and Simmons, {Chad R.} and Nannenga, {Brent L.}",
note = "Funding Information: BLN thanks the Air Force Office of Scientific Research (FA9550‐18‐1–0012) for support of this project. We thank Nathan Henderson for valuable discussions related to the structural work. We acknowledge the use of electron microscopes within the Eyring Materials Center at Arizona State University. This study used beamline 19‐ID at the Advanced Photon Source (APS), a U.S. Department of Energy (DOE) Office of Science User Facility. Funding Information: BLN thanks the Air Force Office of Scientific Research (FA9550-18-1–0012) for support of this project. We thank Nathan Henderson for valuable discussions related to the structural work. We acknowledge the use of electron microscopes within the Eyring Materials Center at Arizona State University. This study used beamline 19-ID at the Advanced Photon Source (APS), a U.S. Department of Energy (DOE) Office of Science User Facility. Publisher Copyright: {\textcopyright} 2021 Wiley Periodicals LLC",
year = "2021",
month = dec,
doi = "10.1002/bit.27927",
language = "English (US)",
volume = "118",
pages = "4867--4873",
journal = "Biotechnology and bioengineering",
issn = "0006-3592",
publisher = "Wiley-VCH Verlag",
number = "12",
}