TY - JOUR
T1 - Spectrum of antimicrobial activity associated with ionic colloidal silver
AU - Morrill, Kira
AU - May, Kathleen
AU - Leek, Daniel
AU - Langland, Nicole
AU - Jeane, La Deana
AU - Ventura, Jose
AU - Skubisz, Corey
AU - Scherer, Sean
AU - Lopez, Eric
AU - Crocker, Ephraim
AU - Peters, Rachel
AU - Oertle, John
AU - Nguyen, Krystine
AU - Just, Scott
AU - Orian, Michael
AU - Humphrey, Meaghan
AU - Payne, David
AU - Jacobs, Bertram
AU - Waters, Robert
AU - Langland, Jeffrey
PY - 2013/3/1
Y1 - 2013/3/1
N2 - Objectives: Silver has historically and extensively been used as a broad-spectrum antimicrobial agent. However, the Food and Drug Administration currently does not recognize colloidal silver as a safe and effective antimicrobial agent. The goal of this study was to further evaluate the antimicrobial efficacy of colloidal silver. Design: Several strains of bacteria, fungi, and viruses were grown under multicycle growth conditions in the presence or absence of ionic colloidal silver in order to assess the antimicrobial activity. Results: For bacteria grown under aerobic or anaerobic conditions, significant growth inhibition was observed, although multiple treatments were typically required. For fungal cultures, the effects of ionic colloidal silver varied significantly between different genera. No viral growth inhibition was observed with any strains tested. Conclusions: The study data support ionic colloidal silver as a broad-spectrum antimicrobial agent against aerobic and anaerobic bacteria, while having a more limited and specific spectrum of activity against fungi.
AB - Objectives: Silver has historically and extensively been used as a broad-spectrum antimicrobial agent. However, the Food and Drug Administration currently does not recognize colloidal silver as a safe and effective antimicrobial agent. The goal of this study was to further evaluate the antimicrobial efficacy of colloidal silver. Design: Several strains of bacteria, fungi, and viruses were grown under multicycle growth conditions in the presence or absence of ionic colloidal silver in order to assess the antimicrobial activity. Results: For bacteria grown under aerobic or anaerobic conditions, significant growth inhibition was observed, although multiple treatments were typically required. For fungal cultures, the effects of ionic colloidal silver varied significantly between different genera. No viral growth inhibition was observed with any strains tested. Conclusions: The study data support ionic colloidal silver as a broad-spectrum antimicrobial agent against aerobic and anaerobic bacteria, while having a more limited and specific spectrum of activity against fungi.
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U2 - 10.1089/acm.2011.0681
DO - 10.1089/acm.2011.0681
M3 - Article
C2 - 23017226
AN - SCOPUS:84875470461
SN - 1075-5535
VL - 19
SP - 224
EP - 231
JO - Journal of Alternative and Complementary Medicine
JF - Journal of Alternative and Complementary Medicine
IS - 3
ER -