SPASER as Nanoprobe for Biological Applications: Current State and Opportunities

Jian Hua Wang, Shao Peng Wang, Pavel N. Melentiev, Victor I. Balykin, Jing Juan Xu, Hong Yuan Chen, Bin Kang

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


Since the concept of surface plasmon amplification by stimulated emission of radiation (SPASER) was proposed in 2003, great progresses have been made on two kinds of plasmonic nanolasers, namely SPASER device and SPASER nanoparticle. In comparison, SPASER nanoparticle, with ultra-narrow emission line, small size, and good biocompatibility, is a kind of promising luminescent nanoprobe and has a bright application prospect in biomedical imaging and sensing. Hence, it is gradually becoming an attractive research hotspot in the world. However, as the research on SPASER nanoparticle is still in its infancy, there are still lots of problems to be solved before it is widely applied. In this paper, the latest research advances of SPASER nanoparticles and their biological applications are reviewed. Besides existing problems, challenges and opportunities of SPASER nanoparticles as next generation luminescent nanoprobes are discussed as well.

Original languageEnglish (US)
Article number2100622
JournalLaser and Photonics Reviews
Issue number7
StatePublished - Jul 2022
Externally publishedYes


  • SPASER nanoparticles
  • luminescent nanoprobes
  • plasmonic nanolasers

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Condensed Matter Physics


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