@inproceedings{6baef7d327094b149a5e74012ea82cfa,
title = "Silicon based pore systems for emerging biosensor applications",
abstract = "Recent research in the domain of single molecule biosensors aims at using silicon pore systems for the electrical detection of charged entities. Detection is achieved through resistive pulse measurements also known as Coulter counting. This work demonstrates the use of silicon based cylindrical micropores which can be used to detect biomolecules with high selectivity and robustness. The micropores used in the experiment were patterned using semiconductor processing techniques to have a final diameter of 5um and a length of 30um on a siliconsubstrate. The probes used in the study were silica beads which have been functionalized to detect two types of protein immunocomplexes: (i) biotin-avidin and (ii) immunoglobulin-G using its specific antibody within the silicon micropore system.",
author = "Trupthi Mathew and Punarvasu Joshi and Shalini Prasad and Michael Goryll and Andreas Spanias and Trevor Thornton",
year = "2010",
doi = "10.1115/IMECE2009-11707",
language = "English (US)",
isbn = "9780791843758",
series = "ASME International Mechanical Engineering Congress and Exposition, Proceedings",
publisher = "American Society of Mechanical Engineers (ASME)",
pages = "263--270",
booktitle = "Proceedings of the ASME International Mechanical Engineering Congress and Exposition 2009, IMECE 2009",
note = "2009 ASME International Mechanical Engineering Congress and Exposition, IMECE2009 ; Conference date: 13-11-2009 Through 19-11-2009",
}