Signaling Endosomes Trigger Synapse Assembly

Jason M. Newbern, Xiaoyan Li, William D. Snider

Research output: Contribution to journalShort surveypeer-review

1 Scopus citations


In this issue of Neuron, Sharma et al. report that target-derived NGF exerts long-distance control of postsynaptic assembly. A major advance is the discovery that TrkA signaling endosomes are retrogradely transported to neuronal dendrites and directly trigger the clustering of postsynaptic density proteins.

Original languageEnglish (US)
Pages (from-to)352-354
Number of pages3
Issue number3
StatePublished - Aug 2010
Externally publishedYes

ASJC Scopus subject areas

  • General Neuroscience


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