Signaling Endosomes Trigger Synapse Assembly

Jason M. Newbern; Xiaoyan Li; William D. Snider

doi:10.1016/j.neuron.2010.07.025

Signaling Endosomes Trigger Synapse Assembly

Jason M. Newbern, Xiaoyan Li, William D. Snider

Research output: Contribution to journal › Short survey › peer-review

1 Scopus citations

Abstract

In this issue of Neuron, Sharma et al. report that target-derived NGF exerts long-distance control of postsynaptic assembly. A major advance is the discovery that TrkA signaling endosomes are retrogradely transported to neuronal dendrites and directly trigger the clustering of postsynaptic density proteins.

Original language	English (US)
Pages (from-to)	352-354
Number of pages	3
Journal	Neuron
Volume	67
Issue number	3
DOIs	https://doi.org/10.1016/j.neuron.2010.07.025
State	Published - Aug 2010
Externally published	Yes

ASJC Scopus subject areas

General Neuroscience

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10.1016/j.neuron.2010.07.025

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title = "Signaling Endosomes Trigger Synapse Assembly",

abstract = "In this issue of Neuron, Sharma et al. report that target-derived NGF exerts long-distance control of postsynaptic assembly. A major advance is the discovery that TrkA signaling endosomes are retrogradely transported to neuronal dendrites and directly trigger the clustering of postsynaptic density proteins.",

author = "Newbern, {Jason M.} and Xiaoyan Li and Snider, {William D.}",

year = "2010",

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pages = "352--354",

journal = "Neuron",

issn = "0896-6273",

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AU - Newbern, Jason M.

AU - Li, Xiaoyan

AU - Snider, William D.

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N2 - In this issue of Neuron, Sharma et al. report that target-derived NGF exerts long-distance control of postsynaptic assembly. A major advance is the discovery that TrkA signaling endosomes are retrogradely transported to neuronal dendrites and directly trigger the clustering of postsynaptic density proteins.

AB - In this issue of Neuron, Sharma et al. report that target-derived NGF exerts long-distance control of postsynaptic assembly. A major advance is the discovery that TrkA signaling endosomes are retrogradely transported to neuronal dendrites and directly trigger the clustering of postsynaptic density proteins.

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DO - 10.1016/j.neuron.2010.07.025

M3 - Short survey

C2 - 20696371

AN - SCOPUS:77955451578

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VL - 67

SP - 352

EP - 354

JO - Neuron

JF - Neuron

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Signaling Endosomes Trigger Synapse Assembly

Abstract

ASJC Scopus subject areas

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