Self-assembling a molecular pegboard

Kyle Lund; Yan Liu; Stuart Lindsay; Hao Yan

doi:10.1021/ja0568446

Self-assembling a molecular pegboard

Kyle Lund, Yan Liu, Stuart Lindsay, Hao Yan

Research output: Contribution to journal › Article › peer-review

103 Scopus citations

Abstract

This paper describes the design, construction, and application of a self-assembled, chemically addressable DNA nanogrid composed of DNA tiles of nanometer dimensions. This self-assembled structure permits precise placement of molecules at predetermined locations on a "molecular pegboard". We used the indexed DNA nanogrids to identify single molecules of DNA that hybridize at particular locations.

Original language	English (US)
Pages (from-to)	17606-17607
Number of pages	2
Journal	Journal of the American Chemical Society
Volume	127
Issue number	50
DOIs	https://doi.org/10.1021/ja0568446
State	Published - Dec 21 2005

ASJC Scopus subject areas

Catalysis
Chemistry(all)
Biochemistry
Colloid and Surface Chemistry

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10.1021/ja0568446

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title = "Self-assembling a molecular pegboard",

abstract = "This paper describes the design, construction, and application of a self-assembled, chemically addressable DNA nanogrid composed of DNA tiles of nanometer dimensions. This self-assembled structure permits precise placement of molecules at predetermined locations on a {"}molecular pegboard{"}. We used the indexed DNA nanogrids to identify single molecules of DNA that hybridize at particular locations.",

author = "Kyle Lund and Yan Liu and Stuart Lindsay and Hao Yan",

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AU - Lindsay, Stuart

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N2 - This paper describes the design, construction, and application of a self-assembled, chemically addressable DNA nanogrid composed of DNA tiles of nanometer dimensions. This self-assembled structure permits precise placement of molecules at predetermined locations on a "molecular pegboard". We used the indexed DNA nanogrids to identify single molecules of DNA that hybridize at particular locations.

AB - This paper describes the design, construction, and application of a self-assembled, chemically addressable DNA nanogrid composed of DNA tiles of nanometer dimensions. This self-assembled structure permits precise placement of molecules at predetermined locations on a "molecular pegboard". We used the indexed DNA nanogrids to identify single molecules of DNA that hybridize at particular locations.

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Self-assembling a molecular pegboard

Abstract

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