Self-assembled peptide nanoarrays: An approach to studying protein-protein interactions

Berea A R Williams; Kyle Lund; Yan Liu; Hao Yan; John C. Chaput

doi:10.1002/anie.200603919

Self-assembled peptide nanoarrays: An approach to studying protein-protein interactions

Berea A R Williams, Kyle Lund, Yan Liu, Hao Yan, John C. Chaput

Research output: Contribution to journal › Article › peer-review

115 Scopus citations

Abstract

(Figure Presented) On show: High-density peptide arrays capable of displaying many different amino acid sequences at well-defined and addressable locations on the same DNA nanostructure have been produced. The strategy used relies on the genetic information encoded in the nucleic acid portion of a DNA-tagged peptide to position the amino acid sequence at a predetermined location on the array.

Original language	English (US)
Pages (from-to)	3051-3054
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	46
Issue number	17
DOIs	https://doi.org/10.1002/anie.200603919
State	Published - 2007

Keywords

DNA
Nanostructures
Peptide nanoarrays
Self-assembly

ASJC Scopus subject areas

Catalysis
Chemistry(all)

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10.1002/anie.200603919

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title = "Self-assembled peptide nanoarrays: An approach to studying protein-protein interactions",

abstract = "(Figure Presented) On show: High-density peptide arrays capable of displaying many different amino acid sequences at well-defined and addressable locations on the same DNA nanostructure have been produced. The strategy used relies on the genetic information encoded in the nucleic acid portion of a DNA-tagged peptide to position the amino acid sequence at a predetermined location on the array.",

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year = "2007",

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AU - Williams, Berea A R

AU - Lund, Kyle

AU - Liu, Yan

AU - Yan, Hao

AU - Chaput, John C.

PY - 2007

Y1 - 2007

N2 - (Figure Presented) On show: High-density peptide arrays capable of displaying many different amino acid sequences at well-defined and addressable locations on the same DNA nanostructure have been produced. The strategy used relies on the genetic information encoded in the nucleic acid portion of a DNA-tagged peptide to position the amino acid sequence at a predetermined location on the array.

AB - (Figure Presented) On show: High-density peptide arrays capable of displaying many different amino acid sequences at well-defined and addressable locations on the same DNA nanostructure have been produced. The strategy used relies on the genetic information encoded in the nucleic acid portion of a DNA-tagged peptide to position the amino acid sequence at a predetermined location on the array.

KW - DNA

KW - Nanostructures

KW - Peptide nanoarrays

KW - Self-assembly

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M3 - Article

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Self-assembled peptide nanoarrays: An approach to studying protein-protein interactions

Abstract

Keywords

ASJC Scopus subject areas

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