Abstract
Sedimentation velocity experiments show that only monomers coexist with amyloid fibrils of human islet amyloidpolypeptide. No oligomers containing >100 monomers could be detected, suggesting that the putative toxic oligomers are much larger than those found for the Alzheimer's peptide, Aβ(1-42).
Original language | English (US) |
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Pages (from-to) | L45-L47 |
Journal | Biophysical journal |
Volume | 94 |
Issue number | 7 |
DOIs | |
State | Published - Apr 2008 |
Externally published | Yes |
ASJC Scopus subject areas
- Biophysics