Safe CRISPR: Challenges and Possible Solutions

Michael Pineda, Ashley Lear, James Collins, Samira Kiani

Research output: Contribution to journalReview articlepeer-review

36 Scopus citations


Applications of CRISPR in human health and in gene drives are at the forefront of biological research as tools. This technology will affect humankind and our environment, so as this technology pushes forward, the design and implementation of safety measures is imperative. Novel technologies and forethought in various applications of CRISPR are essential for using this technology safely. Here, we review environmental and health-related safety concerns associated with using CRISPR and ways proposed to minimize risk.

Original languageEnglish (US)
Pages (from-to)389-401
Number of pages13
JournalTrends in Biotechnology
Issue number4
StatePublished - Apr 2019


  • biosafety
  • gene drives
  • gene therapies

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering


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