TY - JOUR
T1 - Role of B cells in vaccine-induced immunity against coccidioidomycosis
AU - Magee, Dewey
AU - Friedberg, Rhonda L.
AU - Woitaske, Melanie D.
AU - Johnston, Stephen
AU - Cox, Rebecca A.
PY - 2005/10
Y1 - 2005/10
N2 - We investigated secondary immunity against coccidioidomycosis by using gene expression microarrays. Surprisingly, a high percentage of B-cell-related genes were associated with protective immunity. A functional confirmation of the importance of B cells against coccidioidomycosis was achieved by demonstrating that vaccination was not fully protective in B-cell-deficient MuMT mice.
AB - We investigated secondary immunity against coccidioidomycosis by using gene expression microarrays. Surprisingly, a high percentage of B-cell-related genes were associated with protective immunity. A functional confirmation of the importance of B cells against coccidioidomycosis was achieved by demonstrating that vaccination was not fully protective in B-cell-deficient MuMT mice.
UR - http://www.scopus.com/inward/record.url?scp=25444466457&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=25444466457&partnerID=8YFLogxK
U2 - 10.1128/IAI.73.10.7011-7013.2005
DO - 10.1128/IAI.73.10.7011-7013.2005
M3 - Article
C2 - 16177382
AN - SCOPUS:25444466457
SN - 0019-9567
VL - 73
SP - 7011
EP - 7013
JO - Infection and immunity
JF - Infection and immunity
IS - 10
ER -