Ratiometric glucose sensing based on fluorescent oxygen films and glucose oxidase

Fengyu Su, Liqiang Zhang, Xiangxing Kong, Fred Lee, Yanqing Tian, Deirdre Meldrum

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


A new two-layer sensor film was constructed for sensing glucose based on glucose oxidase and oxygen sensing material. The first layer of film containing the oxygen sensor and intra-reference material was polymerized, then the second layer of glucose oxidase and glutaraldehyde was formed on the oxygen sensor layer. The two-layer sensor film has a resolution up to 0.05 mM and a detection range from 0 to 5 mM to glucose. The effects of pH and temperature on the sensing performance were systematically investigated. The selective detection of glucose among other monosaccharides, such as fructose, mannose and galactose indicated that the sensing film has excellent selectivity. The prepared sensor was successfully applied for glucose sample detection of glucose concentration in artificial tears.

Original languageEnglish (US)
Pages (from-to)1-6
Number of pages6
JournalSensing and Bio-Sensing Research
StatePublished - Jun 1 2017


  • Diabetes
  • Fluorescence
  • Glucose oxidase
  • Glucose sensor
  • Oxygen film

ASJC Scopus subject areas

  • Biotechnology
  • Electronic, Optical and Magnetic Materials
  • Signal Processing
  • Electrical and Electronic Engineering


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