Pulmonary-renal syndrome with 'triad' involvement due to small vessel vasculitis

B. N. Doebbeling, S. M. Bonsib, W. P. Walker

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


We describe the clinical course and morphologic findings of a 22-year-old woman presenting with a systemic disease that included nasal ulceration, hemoptysis and rapidly progressive renal failure. Biopsies of nasal septum and lung revealed small vessel leukocytoclastic angiitis while renal biopsy showed a diffuse crescentic glomerulonephritis. Immunosuppressive therapy resulted in remission of clinical symptoms and resolution of glomerulonephritis as documented in a followup biopsy. Although her clinical presentation with triad organ involvement strongly suggested Wegener's granulomatosis, this case illustrates that other varieties of vasculitis may mimic Wegener's granulomatosis.

Original languageEnglish (US)
Pages (from-to)1087-1090
Number of pages4
JournalJournal of Rheumatology
Issue number8
StatePublished - Jan 1 1990
Externally publishedYes


  • Wegener's granulomatosis
  • crescentic glomerulonephritis
  • leukocytoclastic angiitis
  • vasculitis

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology


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