Programmable DMA self-assemblies for nanoscale organization of ligands and proteins

Sung Ha Park; Peng Yin; Yan Liu; John H. Reif; Thomas H. Labean; Hao Yan

doi:10.1021/nl050175c

Programmable DMA self-assemblies for nanoscale organization of ligands and proteins

Sung Ha Park, Peng Yin, Yan Liu, John H. Reif, Thomas H. Labean, Hao Yan

Research output: Contribution to journal › Article › peer-review

259 Scopus citations

Abstract

We demonstrate the precise control of periodic spacing between individual protein molecules by programming the self-assembly of DNA tile templates. In particular, we report the application of two self-assembled periodic DNA structures, two-dimendional nanogrids, and one-dimensional nanotrack, as template for programmable self-assembly of streptavidin protein arrays with controlled density.

Original language	English (US)
Pages (from-to)	729-733
Number of pages	5
Journal	Nano Letters
Volume	5
Issue number	4
DOIs	https://doi.org/10.1021/nl050175c
State	Published - Apr 2005

ASJC Scopus subject areas

Bioengineering
Chemistry(all)
Materials Science(all)
Condensed Matter Physics
Mechanical Engineering

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10.1021/nl050175c

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title = "Programmable DMA self-assemblies for nanoscale organization of ligands and proteins",

abstract = "We demonstrate the precise control of periodic spacing between individual protein molecules by programming the self-assembly of DNA tile templates. In particular, we report the application of two self-assembled periodic DNA structures, two-dimendional nanogrids, and one-dimensional nanotrack, as template for programmable self-assembly of streptavidin protein arrays with controlled density.",

author = "Park, {Sung Ha} and Peng Yin and Yan Liu and Reif, {John H.} and Labean, {Thomas H.} and Hao Yan",

year = "2005",

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doi = "10.1021/nl050175c",

language = "English (US)",

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journal = "Nano Letters",

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AU - Park, Sung Ha

AU - Yin, Peng

AU - Liu, Yan

AU - Reif, John H.

AU - Labean, Thomas H.

AU - Yan, Hao

PY - 2005/4

Y1 - 2005/4

N2 - We demonstrate the precise control of periodic spacing between individual protein molecules by programming the self-assembly of DNA tile templates. In particular, we report the application of two self-assembled periodic DNA structures, two-dimendional nanogrids, and one-dimensional nanotrack, as template for programmable self-assembly of streptavidin protein arrays with controlled density.

AB - We demonstrate the precise control of periodic spacing between individual protein molecules by programming the self-assembly of DNA tile templates. In particular, we report the application of two self-assembled periodic DNA structures, two-dimendional nanogrids, and one-dimensional nanotrack, as template for programmable self-assembly of streptavidin protein arrays with controlled density.

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JO - Nano Letters

JF - Nano Letters

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Programmable DMA self-assemblies for nanoscale organization of ligands and proteins

Abstract

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