Pregnane glycosides from an antitumour fraction of Periploca sepium

Hideji itokawa, Junping Xu, Koichi Takeya

Research output: Contribution to journalArticlepeer-review

39 Scopus citations


Three new pregnane glycosides (S-4a, S-5 and S-10) and two known pregnane glycosides (S-4b and S-6) were isolated from an antitumour fraction of the root barks of Periploca sepium. Their structures were determined by 1H and 13C NMR, FABMS and SIMS spectroscopy and some chemical transformations. One of the glycosides (S-4a) contained the new aglycone Δ5-pregnene-3β,16β,20(R)-triol.

Original languageEnglish (US)
Pages (from-to)1173-1179
Number of pages7
Issue number4
StatePublished - 1988


  • Aselepiadaccae
  • Periploca sepium
  • pregnane glycoside
  • Δ-pregnene-3β,16α,20(S)-triol.
  • Δ-pregnene-3β,16β,20(R)-triol

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Plant Science
  • Horticulture


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