TY - JOUR
T1 - Postexercise Hypotension Is Delayed in Men With Obesity and Hypertension
AU - Jarrett, Catherine L.
AU - Tucker, Wesley J.
AU - Angadi, Siddhartha
AU - Gaesser, Glenn A.
N1 - Funding Information:
This study was partially funded by small grants from the Arizona State University Graduate and Professional Student Association and from Arizona State University—Mayo Clinic Obesity Solutions.
Publisher Copyright:
Copyright © 2022 Jarrett, Tucker, Angadi and Gaesser.
PY - 2022/3/8
Y1 - 2022/3/8
N2 - Background: Postexercise hypotension (PEH) can play a major role in the daily blood pressure management among individuals with hypertension. However, there are limited data on PEH in persons with obesity and hypertension, and no PEH data in this population beyond 90 min postexercise. Purpose: The purpose of this study was to determine if PEH could be elicited in men with obesity and hypertension during a 4-h postexercise measurement period. Methods: Seven men [age = 28 ± 4 years; body mass index = 34.6 ± 4.8 kg/m2; brachial systolic blood pressure (SBP): 138 ± 4 mmHg; brachial diastolic BP (DBP): 80 ± 5 mmHg; central SBP: 125 ± 4 mmHg; central DBP: 81 ± 8 mmHg] performed two exercise sessions on a cycle ergometer, each on a separate day, for 45 min at ∼65% VO2max. One exercise session was performed at a cadence of 45 RPM and one at 90 RPM. Blood pressure was monitored with a SunTech Oscar2 ambulatory blood pressure monitor for 4 h after both exercise sessions, and during a time-matched control condition. Results: Both brachial and central SBP were not changed during the first h postexercise but were reduced by ∼5–11 mmHg between 2 and 4 h postexercise (p < 0.05) after both exercise sessions. Brachial and central DBP were elevated by ∼5 mmHg at 1 h postexercise (p < 0.05) but were ∼2–3 mmHg lower compared to control at 4 h postexercise, and ∼2–4 mmHg lower at 3 h postexercise compared to baseline. Mean arterial pressure (MAP) was elevated compared to control at 1 h postexercise after both exercise sessions, but was ∼2–3 mmHg lower compared to control at 2, 3, and 4 h postexercise, and ∼4–7 mmHg lower at 3 h postexercise compared to baseline. Conclusion: Despite the small sample size and preliminary nature of our results, we conclude that PEH is delayed in men with obesity and hypertension, but the magnitude and duration of PEH up to 4 h postexercise is similar to that reported in the literature for men without obesity and hypertension. The PEH is most pronounced for brachial and central SBP and MAP. The virtually identical pattern of PEH after both exercise trials indicates that the delayed PEH is a reproducible finding in men with obesity and hypertension.
AB - Background: Postexercise hypotension (PEH) can play a major role in the daily blood pressure management among individuals with hypertension. However, there are limited data on PEH in persons with obesity and hypertension, and no PEH data in this population beyond 90 min postexercise. Purpose: The purpose of this study was to determine if PEH could be elicited in men with obesity and hypertension during a 4-h postexercise measurement period. Methods: Seven men [age = 28 ± 4 years; body mass index = 34.6 ± 4.8 kg/m2; brachial systolic blood pressure (SBP): 138 ± 4 mmHg; brachial diastolic BP (DBP): 80 ± 5 mmHg; central SBP: 125 ± 4 mmHg; central DBP: 81 ± 8 mmHg] performed two exercise sessions on a cycle ergometer, each on a separate day, for 45 min at ∼65% VO2max. One exercise session was performed at a cadence of 45 RPM and one at 90 RPM. Blood pressure was monitored with a SunTech Oscar2 ambulatory blood pressure monitor for 4 h after both exercise sessions, and during a time-matched control condition. Results: Both brachial and central SBP were not changed during the first h postexercise but were reduced by ∼5–11 mmHg between 2 and 4 h postexercise (p < 0.05) after both exercise sessions. Brachial and central DBP were elevated by ∼5 mmHg at 1 h postexercise (p < 0.05) but were ∼2–3 mmHg lower compared to control at 4 h postexercise, and ∼2–4 mmHg lower at 3 h postexercise compared to baseline. Mean arterial pressure (MAP) was elevated compared to control at 1 h postexercise after both exercise sessions, but was ∼2–3 mmHg lower compared to control at 2, 3, and 4 h postexercise, and ∼4–7 mmHg lower at 3 h postexercise compared to baseline. Conclusion: Despite the small sample size and preliminary nature of our results, we conclude that PEH is delayed in men with obesity and hypertension, but the magnitude and duration of PEH up to 4 h postexercise is similar to that reported in the literature for men without obesity and hypertension. The PEH is most pronounced for brachial and central SBP and MAP. The virtually identical pattern of PEH after both exercise trials indicates that the delayed PEH is a reproducible finding in men with obesity and hypertension.
KW - blood pressure
KW - body mass index
KW - exercise
KW - obese
KW - overweight
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U2 - 10.3389/fphys.2022.819616
DO - 10.3389/fphys.2022.819616
M3 - Article
AN - SCOPUS:85127260183
SN - 1664-042X
VL - 13
JO - Frontiers in Physiology
JF - Frontiers in Physiology
M1 - 819616
ER -