PD-1 blockade: Rescue from a near-death experience

Joseph N. Blattman; Philip D. Greenberg

doi:10.1038/ni0306-227

PD-1 blockade: Rescue from a near-death experience

Joseph N. Blattman, Philip D. Greenberg

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

It is unclear whether T cell exhaustion is reversible. A recent Nature paper shows that in vivo blockade of the inhibitory molecule PD-1 can restore the function of exhausted CD8⁺ T cells during chronic viral infection.

Original language	English (US)
Pages (from-to)	227-228
Number of pages	2
Journal	Nature Immunology
Volume	7
Issue number	3
DOIs	https://doi.org/10.1038/ni0306-227
State	Published - Mar 2006
Externally published	Yes

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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10.1038/ni0306-227

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title = "PD-1 blockade: Rescue from a near-death experience",

abstract = "It is unclear whether T cell exhaustion is reversible. A recent Nature paper shows that in vivo blockade of the inhibitory molecule PD-1 can restore the function of exhausted CD8+ T cells during chronic viral infection.",

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year = "2006",

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PD-1 blockade: Rescue from a near-death experience

Abstract

ASJC Scopus subject areas

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