TY - JOUR
T1 - Patterns of cocaine use during treatment
T2 - Associations with baseline characteristics and follow-up functioning
AU - Roos, Corey R.
AU - Nich, Charla
AU - Mun, Chung Jung
AU - Mendonca, Justin
AU - Babuscio, Theresa A.
AU - Witkiewitz, Katie
AU - Carroll, Kathleen M.
AU - Kiluk, Brian D.
N1 - Funding Information:
This research was supported by National Institute on Drug Abuse (NIDA) Grants R21DA041661, P50DA009241, and T32DA007238-27 and by NationalInstitute on Alcohol Abuse and Alcoholism(NIAAA) Grant R01 AA022328. NIDA and NIAAA had had no further role in study design; in collection, analysis, or interpretation of data; in the writing of the report; or in the decision to submit the article for publication. *Correspondence may be sent to Corey R. Roos at the Yale University School of Medicine, 40 Temple Street, Suite 6C, New Haven, CT 06510, or via email at: corey.roos@yale.edu.
Publisher Copyright:
© 2019, Alcohol Research Documentation Inc.. All rights reserved.
PY - 2019/7
Y1 - 2019/7
N2 - Objective: Abstinence outcomes are typically prioritized in the treatment of cocaine use disorder while ignoring patterns of low-frequency cocaine use. This study examined patterns of cocaine use frequency during treatment and evaluated how these patterns related to baseline characteristics and functioning outcomes 6and 12 months after treatment. Method: We used a pooled dataset (N =720) from sevenr and omized clinical trials for cocaine use dis order.The Addiction Severity Index(ASI) was used to assess functioning. Repeated-measures latent class analysis was used to derive patterns of cocaine use. Results: Three patterns were identified: abstinence (10.6%), low-frequency use (approximately 1day/week; 66.3%), and persistent frequent use (approximately4days/week; 23.1%).The low-frequency group was as-sociated with male gender, younger age, and a criminal justice referral. The abstinent group had the highest alcohol problem severity score at baseline. At Month 6, the low-frequency group reported lower problem severity than the persistent frequent use group across multiple ASI areas, including the cocaine use as well as psychological, family, employment, and legal domains. At Month 12, the low-frequency group did not differ from the abstinent group in problem severity on any ASI domain and, relative to the persistent frequent use group, had lower cocaine use and employment problem severity. Conclusions: These findings highlight the importance of adopting a harm reduction approach and recognizing the potential clinical benefits associated with non abstinent outcomes.
AB - Objective: Abstinence outcomes are typically prioritized in the treatment of cocaine use disorder while ignoring patterns of low-frequency cocaine use. This study examined patterns of cocaine use frequency during treatment and evaluated how these patterns related to baseline characteristics and functioning outcomes 6and 12 months after treatment. Method: We used a pooled dataset (N =720) from sevenr and omized clinical trials for cocaine use dis order.The Addiction Severity Index(ASI) was used to assess functioning. Repeated-measures latent class analysis was used to derive patterns of cocaine use. Results: Three patterns were identified: abstinence (10.6%), low-frequency use (approximately 1day/week; 66.3%), and persistent frequent use (approximately4days/week; 23.1%).The low-frequency group was as-sociated with male gender, younger age, and a criminal justice referral. The abstinent group had the highest alcohol problem severity score at baseline. At Month 6, the low-frequency group reported lower problem severity than the persistent frequent use group across multiple ASI areas, including the cocaine use as well as psychological, family, employment, and legal domains. At Month 12, the low-frequency group did not differ from the abstinent group in problem severity on any ASI domain and, relative to the persistent frequent use group, had lower cocaine use and employment problem severity. Conclusions: These findings highlight the importance of adopting a harm reduction approach and recognizing the potential clinical benefits associated with non abstinent outcomes.
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U2 - 10.15288/jsad.2019.80.431
DO - 10.15288/jsad.2019.80.431
M3 - Article
C2 - 31495380
AN - SCOPUS:85071896435
SN - 1937-1888
VL - 80
SP - 431
EP - 440
JO - Journal of studies on alcohol and drugs
JF - Journal of studies on alcohol and drugs
IS - 4
ER -