TY - JOUR
T1 - Participation in a social-support physical activity intervention modestly improves lipoprotein cholesterol distribution among postpartum sedentary hispanic women
AU - Vega-Lopez, Sonia
AU - Pignotti, Giselle A P
AU - Keller, Colleen
AU - Todd, Michael
AU - Ainsworth, Barbara
AU - Williams, Allison Nagle
AU - Records, Kathie
AU - Coonrod, Dean
AU - Permana, Paska
N1 - Funding Information:
The authors want to thank Anel Arriola and Crystal Ramos for their contributions toward data collection for this study. Data were collected with support from the National Institutes of Health, National Institute of Nursing Research NIH/NINR 1 R01NR010356-01A2, Madres para la Salud (Mothers for Health) and 3R01NR010356-02S1. Research assistance for data analysis and manuscript development was supported by training funds from the National Institutes of Health, National Institute on Minority Health and Health Disparities (HIH/NIMHD), award P20 MD002316. This material is the result of work supported in part by the Department of Veterans Affairs. The content is solely the responsibility of the authors and does not represent the views of the NIH, the Department of Veterans Affairs, or the United States Government. Clinical Trials Registration Number: NCT01908959.
Publisher Copyright:
© 2015 Human Kinetics, Inc.
PY - 2015/9
Y1 - 2015/9
N2 - Background: The effects of moderate intensity walking on lipoprotein remodeling in postpartum Hispanic women are unknown. Methods: Sedentary postpartum Hispanic women (28.2 ± 5.6 y; BMI = 29.3 ± 3.3 kg/m2) participating in a social support physical activity (PA) intervention, were randomly assigned to a 12-month walking program (walkers; n = 22; target 150 min/wk, moderate intensity) or a control group (nonwalkers; n = 22). Fasting lipids and cholesterol distribution within low-density lipoprotein (LDL) and high-density lipoprotein (HDL) particles were measured at baseline (BL), 6 months, and 12 months. Results: Walkers had an 11% increase and nonwalkers a 7% decrease in HDL cholesterol from 6 to 12 months (P = .0367) without an effect on LDL cholesterol. Whereas nonwalkers had virtually no change in mean LDL particle size, walkers had a borderline reduction in LDL size from BL (268.7 ± 4.1 Å) to 6 months (266.9 ± 4.9 Å), followed by a significant increase in size by 12 months (269.7 ± 4.1 Å; P = .011). The proportion of cholesterol in large LDL particles decreased by 15% from BL to 6 months, but subsequently increased 25% by 12 months among walkers; changes among nonwalkers were smaller and in opposite direction (4% and -3%, respectively; P = .0004). Conclusions: Participation in the social-support PA intervention resulted in slightly increased HDL cholesterol concentrations and a modest and beneficial shift toward larger, less atherogenic LDL particles.
AB - Background: The effects of moderate intensity walking on lipoprotein remodeling in postpartum Hispanic women are unknown. Methods: Sedentary postpartum Hispanic women (28.2 ± 5.6 y; BMI = 29.3 ± 3.3 kg/m2) participating in a social support physical activity (PA) intervention, were randomly assigned to a 12-month walking program (walkers; n = 22; target 150 min/wk, moderate intensity) or a control group (nonwalkers; n = 22). Fasting lipids and cholesterol distribution within low-density lipoprotein (LDL) and high-density lipoprotein (HDL) particles were measured at baseline (BL), 6 months, and 12 months. Results: Walkers had an 11% increase and nonwalkers a 7% decrease in HDL cholesterol from 6 to 12 months (P = .0367) without an effect on LDL cholesterol. Whereas nonwalkers had virtually no change in mean LDL particle size, walkers had a borderline reduction in LDL size from BL (268.7 ± 4.1 Å) to 6 months (266.9 ± 4.9 Å), followed by a significant increase in size by 12 months (269.7 ± 4.1 Å; P = .011). The proportion of cholesterol in large LDL particles decreased by 15% from BL to 6 months, but subsequently increased 25% by 12 months among walkers; changes among nonwalkers were smaller and in opposite direction (4% and -3%, respectively; P = .0004). Conclusions: Participation in the social-support PA intervention resulted in slightly increased HDL cholesterol concentrations and a modest and beneficial shift toward larger, less atherogenic LDL particles.
KW - HDL particles
KW - LDL particles
KW - Randomized controlled trial
KW - Walking
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U2 - 10.1123/jpah.2014-0245
DO - 10.1123/jpah.2014-0245
M3 - Article
C2 - 25408998
AN - SCOPUS:84954211854
SN - 1543-3080
VL - 12
SP - 1289
EP - 1297
JO - Journal of Physical Activity and Health
JF - Journal of Physical Activity and Health
IS - 9
ER -