No-confounding designs with 20 runs—Alternatives to resolution IV screening designs

Brian B. Stone, Douglas Montgomery, Rachel T. Silvestrini, Bradley Jones

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


When experimental resources are significantly constrained, resolution V fractional factorial designs are often prohibitively large for experiments with 6 or more factors. Resolution IV designs may also be cost prohibitive, as additional experimentation may be required to de-alias active 2-factor interactions (2FI). This paper introduces 20-run no-confounding screening designs for 6 to 12 factors as alternatives to resolution IV designs. No-confounding designs have orthogonal main effects, and since no 2FI is completely confounded with another main effects or 2FI, the experimental results can be analyzed without follow-on experimentation. The paper concludes with the results of a Monte Carlo simulation used to assess the model-fitting accuracy of the recommended designs.

Original languageEnglish (US)
Pages (from-to)1861-1872
Number of pages12
JournalQuality and Reliability Engineering International
Issue number8
StatePublished - Dec 2017


  • Monte Carlo simulation
  • experimental design
  • orthogonal array
  • response surface methodology
  • screening designs

ASJC Scopus subject areas

  • Safety, Risk, Reliability and Quality
  • Management Science and Operations Research


Dive into the research topics of 'No-confounding designs with 20 runs—Alternatives to resolution IV screening designs'. Together they form a unique fingerprint.

Cite this