New aerodynamic lens injector for single particle diffractive imaging

Nils Roth; Daniel A. Horke; Jannik Lübke; Amit K. Samanta; Armando D. Estillore; Lena Worbs; Nicolai Pohlman; Kartik Ayyer; Andrew Morgan; Holger Fleckenstein; Martin Domaracky; Benjamin Erk; Christopher Passow; Jonathan Correa; Oleksandr Yefanov; Anton Barty; Saša Bajt; Richard A. Kirian; Henry N. Chapman; Jochen Küpper

doi:10.1016/j.nima.2023.168820

New aerodynamic lens injector for single particle diffractive imaging

Nils Roth, Daniel A. Horke, Jannik Lübke, Amit K. Samanta, Armando D. Estillore, Lena Worbs, Nicolai Pohlman, Kartik Ayyer, Andrew Morgan, Holger Fleckenstein, Martin Domaracky, Benjamin Erk, Christopher Passow, Jonathan Correa, Oleksandr Yefanov, Anton Barty, Saša Bajt, Richard A. Kirian, Henry N. Chapman, Jochen Küpper

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

An aerodynamic lens injector was developed specifically for the needs of single-particle diffractive imaging experiments at free-electron lasers. Its design allows for quick changes of injector geometries and focusing properties in order to optimize injection for specific individual samples. Here, we present results of its first use at the FLASH free-electron-laser facility. Recorded diffraction patterns of polystyrene spheres are modeled using Mie scattering, which allowed for the characterization of the particle beam under diffractive-imaging conditions and yielded good agreement with particle-trajectory simulations. The complex refractive index of polystyrene at λ=4.5nm was determined as m=0.976−0.001i.

Original language	English (US)
Article number	168820
Journal	Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
Volume	1058
DOIs	https://doi.org/10.1016/j.nima.2023.168820
State	Published - Jan 2024
Externally published	Yes

Keywords

Aerodynamic-lens injector
Complex refractive index
Free-electron laser
Polystyrene spheres
Single-particle diffractive imaging

ASJC Scopus subject areas

Nuclear and High Energy Physics
Instrumentation

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10.1016/j.nima.2023.168820

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Roth, N., Horke, D. A., Lübke, J., Samanta, A. K., Estillore, A. D., Worbs, L., Pohlman, N., Ayyer, K., Morgan, A., Fleckenstein, H., Domaracky, M., Erk, B., Passow, C., Correa, J., Yefanov, O., Barty, A., Bajt, S., Kirian, R. A., Chapman, H. N., & Küpper, J. (2024). New aerodynamic lens injector for single particle diffractive imaging. Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 1058, Article 168820. https://doi.org/10.1016/j.nima.2023.168820

Roth, N, Horke, DA, Lübke, J, Samanta, AK, Estillore, AD, Worbs, L, Pohlman, N, Ayyer, K, Morgan, A, Fleckenstein, H, Domaracky, M, Erk, B, Passow, C, Correa, J, Yefanov, O, Barty, A, Bajt, S, Kirian, RA, Chapman, HN & Küpper, J 2024, 'New aerodynamic lens injector for single particle diffractive imaging', Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, vol. 1058, 168820. https://doi.org/10.1016/j.nima.2023.168820

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title = "New aerodynamic lens injector for single particle diffractive imaging",

abstract = "An aerodynamic lens injector was developed specifically for the needs of single-particle diffractive imaging experiments at free-electron lasers. Its design allows for quick changes of injector geometries and focusing properties in order to optimize injection for specific individual samples. Here, we present results of its first use at the FLASH free-electron-laser facility. Recorded diffraction patterns of polystyrene spheres are modeled using Mie scattering, which allowed for the characterization of the particle beam under diffractive-imaging conditions and yielded good agreement with particle-trajectory simulations. The complex refractive index of polystyrene at λ=4.5nm was determined as m=0.976−0.001i.",

keywords = "Aerodynamic-lens injector, Complex refractive index, Free-electron laser, Polystyrene spheres, Single-particle diffractive imaging",

author = "Nils Roth and Horke, {Daniel A.} and Jannik L{\"u}bke and Samanta, {Amit K.} and Estillore, {Armando D.} and Lena Worbs and Nicolai Pohlman and Kartik Ayyer and Andrew Morgan and Holger Fleckenstein and Martin Domaracky and Benjamin Erk and Christopher Passow and Jonathan Correa and Oleksandr Yefanov and Anton Barty and Sa{\v s}a Bajt and Kirian, {Richard A.} and Chapman, {Henry N.} and Jochen K{\"u}pper",

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year = "2024",

month = jan,

doi = "10.1016/j.nima.2023.168820",

language = "English (US)",

volume = "1058",

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AU - Roth, Nils

AU - Horke, Daniel A.

AU - Lübke, Jannik

AU - Samanta, Amit K.

AU - Estillore, Armando D.

AU - Worbs, Lena

AU - Pohlman, Nicolai

AU - Ayyer, Kartik

AU - Morgan, Andrew

AU - Fleckenstein, Holger

AU - Domaracky, Martin

AU - Erk, Benjamin

AU - Passow, Christopher

AU - Correa, Jonathan

AU - Yefanov, Oleksandr

AU - Barty, Anton

AU - Bajt, Saša

AU - Kirian, Richard A.

AU - Chapman, Henry N.

AU - Küpper, Jochen

PY - 2024/1

Y1 - 2024/1

N2 - An aerodynamic lens injector was developed specifically for the needs of single-particle diffractive imaging experiments at free-electron lasers. Its design allows for quick changes of injector geometries and focusing properties in order to optimize injection for specific individual samples. Here, we present results of its first use at the FLASH free-electron-laser facility. Recorded diffraction patterns of polystyrene spheres are modeled using Mie scattering, which allowed for the characterization of the particle beam under diffractive-imaging conditions and yielded good agreement with particle-trajectory simulations. The complex refractive index of polystyrene at λ=4.5nm was determined as m=0.976−0.001i.

AB - An aerodynamic lens injector was developed specifically for the needs of single-particle diffractive imaging experiments at free-electron lasers. Its design allows for quick changes of injector geometries and focusing properties in order to optimize injection for specific individual samples. Here, we present results of its first use at the FLASH free-electron-laser facility. Recorded diffraction patterns of polystyrene spheres are modeled using Mie scattering, which allowed for the characterization of the particle beam under diffractive-imaging conditions and yielded good agreement with particle-trajectory simulations. The complex refractive index of polystyrene at λ=4.5nm was determined as m=0.976−0.001i.

KW - Aerodynamic-lens injector

KW - Complex refractive index

KW - Free-electron laser

KW - Polystyrene spheres

KW - Single-particle diffractive imaging

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ER -

New aerodynamic lens injector for single particle diffractive imaging

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ASJC Scopus subject areas

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