Neuro-dynamic optimal control of a l-lysine fed-batch fermentation

T. Ilkova, M. Petrov, D. Bertsekas

Research output: Contribution to journalArticlepeer-review


In this paper is developed an optimal control of fermentation process of L-lysine production with the Neuro-dynamic programming theory. A approximation neural network is developed and the decision of the optimization problem is improved by an iteration mode founded on the Bellman equation. With this optimization procedure the quantity L-lysine productions is increased at the end of the process.

Original languageEnglish (US)
Pages (from-to)204-207
Number of pages4
JournalBiotechnology and Biotechnological Equipment
Issue number3
StatePublished - Jan 2006
Externally publishedYes

ASJC Scopus subject areas

  • Biotechnology


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