Methylcellulose-laminin conjugate for neural tissue engineering applications: Fabrication and characterization

S. E. Stabenfeldt, M. C. Laplaca

Research output: Chapter in Book/Report/Conference proceedingConference contribution


The fabrication of a novel three-dimensional (3D) neural tissue engineered scaffold composed of a methylcellulose (MC)-laminin (LN) conjugate was investigated. Oxidized MC was treated with 3-(2-pyridyldithio)propionyl hydrazide (PDPH) crosslinker. Rheological parameters were measured on a Bohlin CVO rheometer with a parallel plate configuration. IR-IR spectroscopy verified the formation of dialdehyde groups upon oxidation. The results confirm the conjugation of LN to MC by the heterobifunctional crosslinker PDPH.

Original languageEnglish (US)
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
StatePublished - Dec 1 2004
Externally publishedYes
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: May 17 2004May 21 2004

Publication series

NameTransactions - 7th World Biomaterials Congress


OtherTransactions - 7th World Biomaterials Congress

ASJC Scopus subject areas

  • Engineering(all)


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