TY - JOUR
T1 - Management of primary biliary cirrhosis and autoimmune cholangitis.
AU - Angulo, P.
AU - Lindor, K. D.
PY - 1998/5
Y1 - 1998/5
N2 - Several drugs have been evaluated in the treatment of primary biliary cirrhosis over a number of years. These drugs have immunosuppressive, antiinflammatory, cupruretic, antifibrotic and bile acid properties. Ursodeoxycholic acid has been shown to improve survival free of transplantation in a conclusive fashion. This drug is the single agent that can be recommended for the treatment of primary biliary cirrhosis. Corticosteroid therapy and ursodeoxycholic acid have been evaluated in a few patients with autoimmune cholangitis. This article reviews a large number of studies that have been published assessing different drugs in the treatment of these two entities, particularly in the treatment of primary biliary cirrhosis.
AB - Several drugs have been evaluated in the treatment of primary biliary cirrhosis over a number of years. These drugs have immunosuppressive, antiinflammatory, cupruretic, antifibrotic and bile acid properties. Ursodeoxycholic acid has been shown to improve survival free of transplantation in a conclusive fashion. This drug is the single agent that can be recommended for the treatment of primary biliary cirrhosis. Corticosteroid therapy and ursodeoxycholic acid have been evaluated in a few patients with autoimmune cholangitis. This article reviews a large number of studies that have been published assessing different drugs in the treatment of these two entities, particularly in the treatment of primary biliary cirrhosis.
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U2 - 10.1016/S1089-3261(05)70011-8
DO - 10.1016/S1089-3261(05)70011-8
M3 - Article
C2 - 15560036
AN - SCOPUS:0343199001
SN - 1089-3261
VL - 2
SP - 333-351, ix
JO - Clinics in liver disease
JF - Clinics in liver disease
IS - 2
ER -