Abstract
Finding optimal designs for generalized linear models is a challenging problem. Recent research has identified the structure of optimal designs for generalized linear models with single or multiple unrelated explanatory variables that appear as first-order terms in the predictor. We consider generalized linear models with a single-variable quadratic polynomial as the predictor under a popular family of optimality criteria. When the design region is unrestricted, our results establish that optimal designs can be found within a subclass of designs based on a small support with symmetric structure. We show that the same conclusion holds with certain restrictions on the design region, but in other cases a larger subclass may have to be considered. In addition, we derive explicit expressions for some D-optimal designs.
Original language | English (US) |
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Pages (from-to) | 365-375 |
Number of pages | 11 |
Journal | Biometrika |
Volume | 101 |
Issue number | 2 |
DOIs | |
State | Published - Jun 2014 |
Keywords
- Generalized linear model
- Optimal design
ASJC Scopus subject areas
- Statistics and Probability
- Mathematics(all)
- Agricultural and Biological Sciences (miscellaneous)
- Agricultural and Biological Sciences(all)
- Statistics, Probability and Uncertainty
- Applied Mathematics