Localized Delivery System for Cancer Drug, Phenstatin, Using N-Isopropylacrlyamide

Brent Vernon (Inventor)

Research output: Patent


This invention seeks to improve the delivery of the cancer chemotherapy agent, phenstatin, in the treatment of various bulk cancers using a "smart polymer". Specifically, it involves the design of an injectable drug delivery system to locally deliver phenstatin using temperature based polymers based on N-isopropylacrylamide. The polymer-drug conjugate would be water soluble allowing the system to be injected as a liquid, and subsequently would gel in vivo at the site of delivery.
Original languageEnglish (US)
StatePublished - Jun 20 2002


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