TY - JOUR
T1 - Life stress and lymphocyte alterations among patients with rheumatoid arthritis.
AU - Zautra, A. J.
AU - Okun, M. A.
AU - Kurpius, Sharon
AU - Lee, D.
AU - Roth, S. H.
AU - Emmanual, J.
PY - 1989
Y1 - 1989
N2 - The relation between life stress and immune parameters was investigated for 33 female rheumatoid arthritis (RA) patients interviewed during three routine monthly clinic checkups. Life stress from major and minor events, coping efficacy, and self-reported psychological distress were assessed, and immunofluorescence of T-cells and B-cells was performed on the blood drawn during each visit. Small stressful events were positively related to the proportion of circulating B-cells, psychological distress was inversely related to proportion of circulating T-cells, and major life events were associated with lower T-helper/T-suppressor cell ratios.
AB - The relation between life stress and immune parameters was investigated for 33 female rheumatoid arthritis (RA) patients interviewed during three routine monthly clinic checkups. Life stress from major and minor events, coping efficacy, and self-reported psychological distress were assessed, and immunofluorescence of T-cells and B-cells was performed on the blood drawn during each visit. Small stressful events were positively related to the proportion of circulating B-cells, psychological distress was inversely related to proportion of circulating T-cells, and major life events were associated with lower T-helper/T-suppressor cell ratios.
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U2 - 10.1037/0278-6133.8.1.1
DO - 10.1037/0278-6133.8.1.1
M3 - Article
C2 - 2565227
AN - SCOPUS:0024491024
SN - 0278-6133
VL - 8
SP - 1
EP - 14
JO - Health psychology : official journal of the Division of Health Psychology, American Psychological Association
JF - Health psychology : official journal of the Division of Health Psychology, American Psychological Association
IS - 1
ER -