Diana M. Bowman, Walter G. Johnson, Karinne Ludlow

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript


In the past decade, mitochondrial replacement therapies (MRT) have entered public awareness around the world. These advanced assisted reproductive technologies (ART) primarily promise the means for a small group of families to have a biologically related child without passing on certain heritable mitochondrial diseases. However, these techniques raise safety, social, and ethical issues, which both mirror and depart from concerns raised by ART throughout the past five decades. Regulatory systems for MRT must respond to these concerns while confronting a global context with porous borders, complex stakeholders, and states adopting divergent normative positions. This introductory chapter opens the edited volume, which explores the scientific, social, ethical, and regulatory dimensions of MRT from various disciplinary and geographic perspectives. The chapters that follow seek to aid policymakers and communities in identifying the ethical, legal, and societal norms or decisions they must address as more people seek to access these treatments.

Original languageEnglish (US)
Title of host publicationReproduction Reborn
Subtitle of host publicationHow Science, Ethics, and Law Shape Mitochondrial Replacement Therapies
PublisherOxford University Press
Number of pages16
ISBN (Electronic)9780197616192
ISBN (Print)9780197616208
StatePublished - Jan 1 2023
Externally publishedYes


  • assisted reproductive technologies
  • ethics
  • governance
  • mitochondrial replacement therapies
  • regulation

ASJC Scopus subject areas

  • General Medicine


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