Intracellular localization of titanium dioxide-biomolecule nanocomposites

T. Paunesku, N. Stojicevic, S. Vogt, J. Maser, B. Lai, T. Rajh, M. Thurnauer, G. Woloschak

Research output: Contribution to journalConference articlepeer-review

7 Scopus citations


Emerging areas of nanotechnology hold the promise of overcoming the limitations of existing technology for intracellular manipulation. These new developments include the creation of nanocomposites that can be introduced into the cells, targeted to specific subcellular sites, and subsequently used as platforms for initiation of intracellular processes dependent on or aided by locally high concentrations of specific molecules delivered as components of the nanocomposites. Nanocomposites that combine functional properties of biomolecules with the functional properties of inorganic components could provide new tools for biology, medicine, chemistry and material sciences. Here we describe how we introduced TiO2-DNA nanocomposites into cells, and localized titanium in the cells by mapping the Ti Kα X-ray fluorescence induced at the 2-ID-E microprobe of the SRI-CAT at the Advanced Photon Source at Argonne National Laboratory.

Original languageEnglish (US)
Pages (from-to)317-319
Number of pages3
JournalJournal De Physique. IV : JP
StatePublished - Mar 2003
Externally publishedYes
Event7th International Conference on X-Ray Microscopy - Grenoble, France
Duration: Jul 28 2002Aug 2 2002

ASJC Scopus subject areas

  • General Physics and Astronomy


Dive into the research topics of 'Intracellular localization of titanium dioxide-biomolecule nanocomposites'. Together they form a unique fingerprint.

Cite this