TY - JOUR
T1 - Intergenerational transmission of ancestry information in a mid-size city in Argentina
AU - Mendoza, Marcela
AU - Mazza, Bárbara
AU - Cabana, Graciela S.
AU - Smith, Lindsay
AU - Di Fabio Rocca, Francisco
AU - Delfino, Hugo
AU - Martínez, Carla
N1 - Funding Information:
The work was supported by the National Science Foundation [SES-1354185] The anonymized data analyzed here were collected during a research project in Argentina entitled “A longitudinal study of the role of expert knowledge in the interpretation and reception of genetic information”. It was part of the National Science Foundation Senior Research Grant Award No. SES-1354185 (https://nsf.gov/awardsearch/showAward?AWD_ID=1354185). All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2000 (5). Informed consent was obtained from all participants in the study. The U.S. National Science Foundation, the Institutional Review Board (IRB) at the Universities of Tennessee, Oregon, and New Mexico, and the Comité de Ética de la Región Sanitaria VII Hospital de Agudos ‘Dr. Ramón Carrillo’ in Ciudadela, Argentina, evaluated and approved this project. Marcela Mendoza, Bárbara Mazza, Graciela S. Cabana, Lindsay Smith, Francisco Di Fabio Rocca, Hugo Delfino, and Carla Martínez declare that they have no conflict of interest. This article benefited from feedback from the participants in a Western Michigan University research brief organized on February 23, 2021. We are grateful for the insightful comments on a previous version by four anonymous reviewers. Following the preference expressed by Indigenous scholars, throughout the paper we chose to capitalize the term Indigenous Peoples
Funding Information:
The anonymized data analyzed here were collected during a research project in Argentina entitled “A longitudinal study of the role of expert knowledge in the interpretation and reception of genetic information”. It was part of the National Science Foundation Senior Research Grant Award No. SES-1354185 ( https://nsf.gov/awardsearch/showAward?AWD_ID=1354185 ). All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2000 (5). Informed consent was obtained from all participants in the study. The U.S. National Science Foundation, the Institutional Review Board (IRB) at the Universities of Tennessee, Oregon, and New Mexico, and the Comité de Ética de la Región Sanitaria VII Hospital de Agudos ‘Dr. Ramón Carrillo’ in Ciudadela, Argentina, evaluated and approved this project. Marcela Mendoza, Bárbara Mazza, Graciela S. Cabana, Lindsay Smith, Francisco Di Fabio Rocca, Hugo Delfino, and Carla Martínez declare that they have no conflict of interest. This article benefited from feedback from the participants in a Western Michigan University research brief organized on February 23, 2021. We are grateful for the insightful comments on a previous version by four anonymous reviewers. Following the preference expressed by Indigenous scholars, throughout the paper we chose to capitalize the term Indigenous Peoples
Publisher Copyright:
© 2022 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2023
Y1 - 2023
N2 - We examined the self-reported family trees of 288 adult Argentines from a mid-size city near Buenos Aires to evaluate how intergenerational transmission of ancestry information matched (or not) anonymized estimates of continental-level genetic ancestry. Intergenerational transmission of ancestry information was inferred from the content of the anonymized family trees, and continental-level ancestries were inferred from genomic information collected from the participants. We found a high degree of concordance between genetic ancestry estimates and the transmission of ancestry information in ancestors born in Europe, the Middle East, and Southeast Asia. We found the reverse in ancestors who were Indigenous American, sub-Saharan African, or their descendants. Yet, the existence of those ancestors was evident in the genetic ancestry estimates. We extrapolated the presence of such ancestries in family trees post hoc by deducing that some ancestors identified as ‘Argentine’ in family trees were likely of mixed Indigenous- and non-Indigenous-descent, and possibly also sub-Saharan African descent. We describe these findings as products of a process of attrition, in which some ancestries, but not others, have been forgotten (knowingly or unknowingly) over the course of generations, to the point that participants were unaware that ethno-racial mixing occurred within their own families.
AB - We examined the self-reported family trees of 288 adult Argentines from a mid-size city near Buenos Aires to evaluate how intergenerational transmission of ancestry information matched (or not) anonymized estimates of continental-level genetic ancestry. Intergenerational transmission of ancestry information was inferred from the content of the anonymized family trees, and continental-level ancestries were inferred from genomic information collected from the participants. We found a high degree of concordance between genetic ancestry estimates and the transmission of ancestry information in ancestors born in Europe, the Middle East, and Southeast Asia. We found the reverse in ancestors who were Indigenous American, sub-Saharan African, or their descendants. Yet, the existence of those ancestors was evident in the genetic ancestry estimates. We extrapolated the presence of such ancestries in family trees post hoc by deducing that some ancestors identified as ‘Argentine’ in family trees were likely of mixed Indigenous- and non-Indigenous-descent, and possibly also sub-Saharan African descent. We describe these findings as products of a process of attrition, in which some ancestries, but not others, have been forgotten (knowingly or unknowingly) over the course of generations, to the point that participants were unaware that ethno-racial mixing occurred within their own families.
KW - Argentina
KW - Family trees
KW - attrition
KW - ethno-racial mixing
KW - genetic ancestry
UR - http://www.scopus.com/inward/record.url?scp=85139105488&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85139105488&partnerID=8YFLogxK
U2 - 10.1080/17442222.2022.2120730
DO - 10.1080/17442222.2022.2120730
M3 - Article
AN - SCOPUS:85139105488
SN - 1744-2222
VL - 18
SP - 415
EP - 436
JO - Latin American and Caribbean Ethnic Studies
JF - Latin American and Caribbean Ethnic Studies
IS - 3
ER -