The Greenland Telescope project will deploy and operate a 12m sub-millimeter telescope at the highest point of the Greenland i e sheet. The Greenland Telescope project is a joint venture between the Smithsonian As-trophysical Observatory (SAO) and the Academia Sinica Institute of Astronomy and Astrophysics (ASIAA). In this paper we discuss the concepts, specifications, and science goals of the instruments being developed for single-dish observations with the Greenland Telescope, and the coupling optics required to couple both them and the mm-VLBI receivers to antenna. The project will outfit the ALMA North America prototype antenna for Arctic operations and deploy it to Summit Station,1 a NSF operated Arctic station at 3,100m above MSL on the Greenland I e Sheet. This site is exceptionally dry, and promises to be an excellent site for sub-millimeter astronomical observations. The main science goal of the Greenland Telescope is to carry out millimeter VLBI observations alongside other telescopes in Europe and the Americas, with the aim of resolving the event horizon of the super-massive black hole at the enter of M87. The Greenland Telescope will also be outfitted for single-dish observations from the millimeter-wave to Tera-hertz bands. In this paper we will discuss the proposed instruments that are currently in development for the Greenland Telescope-350 GHz and 650 GHz heterodyne array receivers; 1.4 THz HEB array receivers and a W-band bolometric spectrometer. SAO is leading the development of two heterodyne array instruments for the Greenland Telescope, a 48-pixel, 325-375 GHz SIS array receiver, and a 4 pixel, 1.4 THz HEB array receiver. A key science goal for these instruments is the mapping of ortho and para H2D+ in old protostellar ores, as well as general mapping of CO and other transitions in molecular louds. An 8-pixel prototype module for the 350 GHz array is currently being built for laboratory and operational testing on the Greenland Telescope. Arizona State University are developing a 650 GHz 256 pixel SIS array receiver based on the KAPPa SIS mixer array technology and ASIAA are developing 1.4 THz HEB single pixel and array receivers. The University of Cambridge and SAO are collaborating on the development of the CAMbridge Emission Line Surveyor (CAMELS), a W-band 'on-hip' spectrometer instrument with a spectral resolution of R ∼ 3000. CAMELS will consist of two pairs of horn antennas, feeding super conducting niobium nitride filter banks read by tantalum based Kinetic Inductance Detectors.