Abstract
Demethylation of 2,3-dimethoxy-6-bromobenzoic acid in hydrogen bromide-acetic acid solution was shown to yield 2,3-dihydroxy-5-bromobenzoic acid. Under similar conditions, 3,4-dimethoxy-6-bromonitrobenzene was found to yield substantial amounts of the unrearranged product of demethylation, 3,4-dihydroxy-6-bromonitrobenzene, accompanied by 3,4-dihydroxynitrobenzene. The structural and environmental features which appear to influence halogen migration in the bromohydroxybenzoic series are summarized.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 721-725 |
| Number of pages | 5 |
| Journal | Journal of Organic Chemistry |
| Volume | 25 |
| Issue number | 5 |
| DOIs | |
| State | Published - Jan 1 1960 |
| Externally published | Yes |
ASJC Scopus subject areas
- Organic Chemistry