Home chemical and microbial transitions across urbanization

Laura Isobel McCall; Chris Callewaert; Qiyun Zhu; Se Jin Song; Amina Bouslimani; Jeremiah J. Minich; Madeleine Ernst; Jean F. Ruiz-Calderon; Humberto Cavallin; Henrique S. Pereira; Atila Novoselac; Jean Hernandez; Rafael Rios; Ora Lee H. Branch; Martin J. Blaser; Luciana C. Paulino; Pieter C. Dorrestein; Rob Knight; Maria G. Dominguez-Bello

doi:10.1038/s41564-019-0593-4

Home chemical and microbial transitions across urbanization

Laura Isobel McCall, Chris Callewaert, Qiyun Zhu, Se Jin Song, Amina Bouslimani, Jeremiah J. Minich, Madeleine Ernst, Jean F. Ruiz-Calderon, Humberto Cavallin, Henrique S. Pereira, Atila Novoselac, Jean Hernandez, Rafael Rios, Ora Lee H. Branch, Martin J. Blaser, Luciana C. Paulino, Pieter C. Dorrestein, Rob Knight, Maria G. Dominguez-Bello

Research output: Contribution to journal › Letter › peer-review

75 Scopus citations

Abstract

Urbanization represents a profound shift in human behaviour, and has considerable cultural and health-associated consequences^1,2. Here, we investigate chemical and microbial characteristics of houses and their human occupants across an urbanization gradient in the Amazon rainforest, from a remote Peruvian Amerindian village to the Brazilian city of Manaus. Urbanization was found to be associated with reduced microbial outdoor exposure, increased contact with housing materials, antimicrobials and cleaning products, and increased exposure to chemical diversity. The degree of urbanization correlated with changes in the composition of house bacterial and microeukaryotic communities, increased house and skin fungal diversity, and an increase in the relative abundance of human skin-associated fungi and bacteria in houses. Overall, our results indicate that urbanization has large-scale effects on chemical and microbial exposures and on the human microbiota.

Original language	English (US)
Pages (from-to)	108-115
Number of pages	8
Journal	Nature Microbiology
Volume	5
Issue number	1
DOIs	https://doi.org/10.1038/s41564-019-0593-4
State	Published - Jan 1 2020
Externally published	Yes

ASJC Scopus subject areas

Microbiology
Immunology
Applied Microbiology and Biotechnology
Genetics
Microbiology (medical)
Cell Biology

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10.1038/s41564-019-0593-4

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McCall, L. I., Callewaert, C., Zhu, Q., Song, S. J., Bouslimani, A., Minich, J. J., Ernst, M., Ruiz-Calderon, J. F., Cavallin, H., Pereira, H. S., Novoselac, A., Hernandez, J., Rios, R., Branch, O. L. H., Blaser, M. J., Paulino, L. C., Dorrestein, P. C., Knight, R., & Dominguez-Bello, M. G. (2020). Home chemical and microbial transitions across urbanization. Nature Microbiology, 5(1), 108-115. https://doi.org/10.1038/s41564-019-0593-4

McCall, LI, Callewaert, C, Zhu, Q, Song, SJ, Bouslimani, A, Minich, JJ, Ernst, M, Ruiz-Calderon, JF, Cavallin, H, Pereira, HS, Novoselac, A, Hernandez, J, Rios, R, Branch, OLH, Blaser, MJ, Paulino, LC, Dorrestein, PC, Knight, R & Dominguez-Bello, MG 2020, 'Home chemical and microbial transitions across urbanization', Nature Microbiology, vol. 5, no. 1, pp. 108-115. https://doi.org/10.1038/s41564-019-0593-4

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abstract = "Urbanization represents a profound shift in human behaviour, and has considerable cultural and health-associated consequences1,2. Here, we investigate chemical and microbial characteristics of houses and their human occupants across an urbanization gradient in the Amazon rainforest, from a remote Peruvian Amerindian village to the Brazilian city of Manaus. Urbanization was found to be associated with reduced microbial outdoor exposure, increased contact with housing materials, antimicrobials and cleaning products, and increased exposure to chemical diversity. The degree of urbanization correlated with changes in the composition of house bacterial and microeukaryotic communities, increased house and skin fungal diversity, and an increase in the relative abundance of human skin-associated fungi and bacteria in houses. Overall, our results indicate that urbanization has large-scale effects on chemical and microbial exposures and on the human microbiota.",

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AU - McCall, Laura Isobel

AU - Callewaert, Chris

AU - Zhu, Qiyun

AU - Song, Se Jin

AU - Bouslimani, Amina

AU - Minich, Jeremiah J.

AU - Ernst, Madeleine

AU - Ruiz-Calderon, Jean F.

AU - Cavallin, Humberto

AU - Pereira, Henrique S.

AU - Novoselac, Atila

AU - Hernandez, Jean

AU - Rios, Rafael

AU - Branch, Ora Lee H.

AU - Blaser, Martin J.

AU - Paulino, Luciana C.

AU - Dorrestein, Pieter C.

AU - Knight, Rob

AU - Dominguez-Bello, Maria G.

PY - 2020/1/1

Y1 - 2020/1/1

N2 - Urbanization represents a profound shift in human behaviour, and has considerable cultural and health-associated consequences1,2. Here, we investigate chemical and microbial characteristics of houses and their human occupants across an urbanization gradient in the Amazon rainforest, from a remote Peruvian Amerindian village to the Brazilian city of Manaus. Urbanization was found to be associated with reduced microbial outdoor exposure, increased contact with housing materials, antimicrobials and cleaning products, and increased exposure to chemical diversity. The degree of urbanization correlated with changes in the composition of house bacterial and microeukaryotic communities, increased house and skin fungal diversity, and an increase in the relative abundance of human skin-associated fungi and bacteria in houses. Overall, our results indicate that urbanization has large-scale effects on chemical and microbial exposures and on the human microbiota.

AB - Urbanization represents a profound shift in human behaviour, and has considerable cultural and health-associated consequences1,2. Here, we investigate chemical and microbial characteristics of houses and their human occupants across an urbanization gradient in the Amazon rainforest, from a remote Peruvian Amerindian village to the Brazilian city of Manaus. Urbanization was found to be associated with reduced microbial outdoor exposure, increased contact with housing materials, antimicrobials and cleaning products, and increased exposure to chemical diversity. The degree of urbanization correlated with changes in the composition of house bacterial and microeukaryotic communities, increased house and skin fungal diversity, and an increase in the relative abundance of human skin-associated fungi and bacteria in houses. Overall, our results indicate that urbanization has large-scale effects on chemical and microbial exposures and on the human microbiota.

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JO - Nature Microbiology

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Home chemical and microbial transitions across urbanization

Abstract

ASJC Scopus subject areas

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