High resolution mass spectrometry. Bufadienolides—II.

Peter Brown, Yoshiaki Kamano, George Pettit

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Complete low resolution mass spectra and high resolution data for selected important peaks are presented and discussed for a series of naturally occurring 14β, 15β‐epoxybufadienolides (toad poisons) and their derivatives. The compounds examined were resibufogenin, marinobufagin, cinobufagin, desacetylcinobufagin, cinobufotalin, desacetylcinobufotalin and resibufagin, and the derivatives were 11α‐hydroxyresibufogenin, 3β‐acetoxymarinobufagin, 3‐ketocinobufagin, 3β‐acetoxy‐16β‐desacetylcinobufagin, 3β‐acetoxy‐16‐ketocinobufagin, resibufaginol, 14α‐artebufogenin and 3β‐suberyloxyresibufogenin methyl ester. The relatively unsaturated 2‐pyrone group of C‐17β has been used as an integral label to distinguish (from elemental composition data) ions containing it from those arising in other parts of the molecule that do not, and the spectra are interpreted in terms of structural ‘ion types’.

Original languageEnglish (US)
Pages (from-to)613-646
Number of pages34
JournalOrganic Mass Spectrometry
Issue number6
StatePublished - 1972

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Instrumentation


Dive into the research topics of 'High resolution mass spectrometry. Bufadienolides—II.'. Together they form a unique fingerprint.

Cite this