Genomic signatures of sex-biased demography: progress and prospects

Timothy H. Webster, Melissa Wilson Sayres

Research output: Contribution to journalReview articlepeer-review

23 Scopus citations


Sex-biased demographic events have played a crucial role in shaping human history. Many of these processes affect genetic variation and can therefore leave detectable signatures in the genome because autosomal, X-linked, Y-linked, and mitochondrial DNA inheritance differ between sexes. Here, we discuss how sex-biased processes shape patterns of genetic diversity across the genome, review recent genomic evidence for sex-biased demography in modern human populations, and suggest directions for future research.

Original languageEnglish (US)
Pages (from-to)62-71
Number of pages10
JournalCurrent Opinion in Genetics and Development
StatePublished - Dec 1 2016

ASJC Scopus subject areas

  • Genetics
  • Developmental Biology


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