Genetic rescue guidelines with examples from Mexican wolves and Florida panthers

Philip W. Hedrick, Richard Fredrickson

Research output: Contribution to journalArticlepeer-review

229 Scopus citations


In populations or species with low fitness (high genetic load), a new management strategy called genetic rescue has been advocated to help avoid extinction. In this strategy, unrelated individuals from another population are introduced into the population with low fitness in an effort to reduce genetic load. Here we present ten guidelines that can be used to evaluate when genetic rescue is a good management option, the appropriate procedures for genetic rescue planning and management, and the potential negative genetic consequences of genetic rescue. These guidelines are then used to evaluate the genetic rescue aspects of the recovery programs for the Mexican wolf and the Florida panther.

Original languageEnglish (US)
Pages (from-to)615-626
Number of pages12
JournalConservation Genetics
Issue number2
StatePublished - 2010


  • Florida panthers
  • Gene flow
  • Genetic load
  • Genetic restoration
  • Inbreeding depression
  • Mexican wolves

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Genetics


Dive into the research topics of 'Genetic rescue guidelines with examples from Mexican wolves and Florida panthers'. Together they form a unique fingerprint.

Cite this