Genetic regulation of somite and early spinal patterning

Kenro Kusumi, Walter Eckalbar, Olivier Pourquié

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


The spine plays an essential biomechanical role, and disruptions to the structure of the vertebral column can have profound clinical consequences. The structure of the spine is patterned early in embryonic development with the formation of transient segmental structures called somites. Developmental studies have helped to identify the genetic pathways regulating this process and the mutations that lead to severe congenital vertebral.

Original languageEnglish (US)
Title of host publicationThe Genetics and Development of Scoliosis
PublisherSpringer New York
Number of pages20
ISBN (Electronic)9781441914064
ISBN (Print)9781441914057
StatePublished - Jan 1 2010

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)


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