Four-cluster analysis: A simple method to test phylogenetic hypotheses

Andrey Rzhetsky, Sudhir Kumar, Masatoshi Nei

Research output: Contribution to journalArticlepeer-review

33 Scopus citations


A simple statistical test for comparing three alternative phylogenetic hypotheses for four monophyletic groups is presented. This test is based on the minimum-evolution principle, and it does not require any information regarding the branching order within each monophyletic group. It is computationally efficient and can be easily extended to five or more monophyletic groups.

Original languageEnglish (US)
Pages (from-to)163-167
Number of pages5
JournalMolecular biology and evolution
Issue number1
StatePublished - Jan 1995

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Molecular Biology
  • Genetics


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